It distorts the sharp, central vision needed to see fine details such as for reading and driving. Another was that lycopene-rich foods often contain other cancer-protective compounds, so it would be difficult to isolate any health benefits to lycopeneĪge-related macular degeneration (AMD) is a common painless eye condition but a leading cause of vision loss among people age 50 and older. However, an FDA review stated that definite conclusions about lycopene could not be made, one reason being that accurate reporting of lycopene intake is difficult due to variations in lycopene content during cooking and storage. A 2015 meta-analysis of 26 studies found that higher lycopene intakes appeared protective from prostate cancer incidence. A Harvard study of more than 51,000 men from the Health Professionals Follow-up Study found a protective effect from advanced stages of prostate cancer in those with higher intakes of tomato sauce. Observational studies and clinical trials have shown either a protective effect of lycopene-rich foods (specifically tomatoes) or supplements, or no effect. Unfortunately, studies have not provided a clear answer specific to lycopene. Observational studies have noted a decreased risk of prostate cancer in men who eat high amounts of fruits and vegetables. There has been interest in lycopene’s effects on cancer due to its antioxidant properties. Prostate Cancer: Lycopene is a carotenoid that gives fruits and vegetables a pink or red hue, as in tomatoes and grapefruit. Preventive Services Task Force advises against the use of beta-carotene supplements for the prevention of any cancer, stating that there is potentially greater harm in using these supplements than any suggested benefit. Additionally, based on current evidence the U.S. Therefore, it is recommended that current or former smokers and workers exposed to asbestos do not use high-dose beta-carotene and retinyl palmitate supplements. In fact, two of those three trials actually found a significant increase in lung cancer risk among study participants taking supplements with beta-carotene or retinyl palmitate (a form of vitamin A). However, three large clinical trials did not find that supplements of beta-carotene and vitamin A helped to prevent or reduce lung cancer risk. Lung Cancer: Observational studies following nonsmokers and current or former smokers have found that higher intakes of carotenoids from fruits and vegetables are associated with a lower risk of lung cancer. The evidence suggests that eating a variety of foods rich in vitamin A, especially fruits and vegetables, is protective from certain diseases, though the health benefit of vitamin A supplements is less clear. The UL for vitamin A from retinol is 3,000 micrograms of preformed vitamin A.
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